What evidence is there that The Akkermansia Company™ supplements work best when taken for three months?

There are several studies taking place where Akkermansia efficacy data is available highlighting results in those taking the product for between 3 to 6 months. The proof-of-concept study, where participants took the product for 3 months, indicates an effect on metabolic syndrome with prediabetes and/or lipid
disorders in the blood and obesity.

Can The Akkermansia Company™ supplements be stored at room temperature?

Yes, our products can be stored at room temperature. It does not need to be kept in the refrigerator.

When is the best time to take The Akkermansia Company™ Healthy Weight?

We advise that our Healthy Weight product is taken alongside a meal, ideally breakfast.

Why is Akkermansia pasteurised?

Our preclinical studies and proof of concept trial* found that the pasteurised form of Akkermansia MucT™ was even more beneficial than the live strain with regards to its effect on gut barrier function, insulin sensitivity, fat mass composition, dyslipidaemia and immune homeostasis.

Pasteurizing Akkermansia muciniphila MucT™ turns it from a probiotic into a postbiotic. Probiotics are less stable, leaving them vulnerable to oxygen, stomach acid, and bile salts. Postbiotics reach your small intestine and colon more effectively due to their increased stability.

Our pasteurized Akkermansia MucT™ gets to your gut more effectively and in greater quantity than live Akkermansia MucT™ products, making it the most bio-efficacious Akkermansia MucT™ supplement.

Can The Akkermansia Company™ products be taken with other products that support the gut?

Yes, Akkermansia can be taken alongside other products. Akkermansia in its pasteurised form is active in the gut without any known enzymatic drug-microbiome interactions and is subsequently excreted in the stool. As a result, it doesn’t interfere with the metabolism of any drug that is absorbed into the body. It is worth noting, however, that EGCG, a green tea component, can hamper iron absorption.

Is Akkermansia suitable for vegans?

Yes, Akkermansia is suitable for both vegetarians and vegans. It is also free of lactose, gluten and has no GMOs.

REFERENCES

*for more information visit our clinical studies page. 

  1.  Depommier, C., et al. (2019). “Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.” Nat Med 25(7): 1096-1103.
  2.  Plovier, H., et al. (2017). “A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.” Nat Med 23(1): 107-113.
  3.  Wen, J. J., et al. (2023). “Tea polyphenol and epigallocatechin gallate ameliorate hyperlipidemia via regulating liver metabolism and remodeling gut microbiota.” Food Chem 404(Pt A): 134591.